PhD Candidate in Materials Science and Engineering, Whiting School of Engineering

Chenhu received his B.S. in Chemical Biology from Peking University in 2016. His thesis research focuses on encapsulation and controlled release of protein and peptide drugs such as insulin-like growth factor I (IGF-1), glia maturation factor β (GMF-β), antibodies, and semaglutide into biodegradable nanoparticles using the flash nanocomplexation (FNC) process as a continuous manufacturing method.  His research aims to apply these nanotherapeutics for treatment of peripheral nerve injuries and other diseases. 

Publications: 

• Li S, Hu Y, Li A, Lin J, Hsieh K, Schneiderman Z, Zhang P, Zhu Y, Qiu C, Kokkoli E, Wang TH, Mao HQ. Payload distribution and capacity of mRNA lipid nanoparticles. Nat Commun. 2022 Sep; 13(1): 5561. PMID: 36151112.
• Hanwright PJ*, Qiu C*, Rath J, Zhou Y, von Guionneau N, Sarhane KA, Harris TGW, Howard GP, Malapati H, Lan MJ, Reddy S, Hoke A, Mao HQ, Tuffaha SH. Sustained IGF-1 delivery ameliorates effects of chronic denervation and improves functional recovery after peripheral nerve injury and repair. Biomaterials. 2022 Jan; 280: 121244. PMID: 34794826.
• Slavin BR, Sarhane KA, von Guionneau N, Hanwright PJ, Qiu C, Mao HQ, Höke A, Tuffaha SH. Insulin-like growth factor-1: A promising therapeutic target for peripheral nerve injury. Front Bioeng Biotechnol. 2021 Jun; 9: 695850. PMID: 34249891.